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Symbol Name ID |
Lepr
leptin receptor MGI:104993 |
| Darker colors indicate more annotations |
| Human Phenotypes | Premature coronary artery atherosclerosis |
Hypertension |
Sudden cardiac death |
Myocardial infarction |
| Disease(s) Associated with LEPR | ||||
| coronary artery disease |
| Mouse Phenotypes | abnormal aorta morphology |
abnormal vascular development |
abnormal myocardium layer morphology |
abnormal myocardial fiber morphology |
heart left ventricle hypertrophy |
decreased heart weight |
abnormal cardiovascular system physiology |
abnormal blood circulation |
decreased cardiac output |
cardiac ischemia |
decreased cardiac muscle contractility |
increased left ventricle diastolic pressure |
decreased heart rate |
abnormal response to cardiac infarction |
decreased systemic arterial blood pressure |
decreased systemic arterial systolic blood pressure |
increased mean systemic arterial blood pressure |
increased vasoconstriction |
abnormal vascular wound healing |
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| Availability | Mouse Genotype | |||||||||||||||||||
| Leprdb-lb/Leprdb-lb | ||||||||||||||||||||
| Leprdb/Leprdb | ||||||||||||||||||||
| Leprm8Btlr/Leprm8Btlr | ||||||||||||||||||||
| Leprtm1b(EUCOMM)Wtsi/Leprtm1b(EUCOMM)Wtsi | ||||||||||||||||||||
| Leprtm1Mgmj/Leprtm1Mgmj | ||||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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